![]() In this article, learn about the possible causes for pupils of different sizes, as well as when to see a doctor. Anisocoria is a symptom of many conditions but is not a condition on its own. The medical term for pupils of different sizes is anisocoria. What is the medical term for different sizes of pupils? Another possible cause is Adie’s tonic pupil syndrome. ![]() the iris tissue) can be injured causing the pupil to not get small (or constrict) to bright light normally. What are some causes of an abnormally large (dilated or mydriatic) pupil? After trauma to the eye, the colored part of the eye (i.e. What causes an abnormally large pupil in the eye? When they do not, the pupils may appear to be different sizes. Usually, the pupils in each eye dilate or constrict at the same time. Is it normal to have pupils of different sizes? 1: The iris is the colored part of the eye. When in a bright room or outdoors the pupil usually gets smaller (or constricts) conversely when in a dark room the pupil usually gets bigger (or dilates) to allow more light to enter the eye. The scientists speculate that smaller pupil size during deep sleep serves a protective function of maintaining sleep stability even if ambient light brightens. ![]() The researchers found that the parasympathetic nervous system drives changes in pupil size during non-rapid eye movement (NREM) deep sleep. Why are my pupils so small when I wake up? The muscles themselves may tire and the ability to keep the pupil open may fade. Moreover, your pupils’ overall size will shrink, perhaps reflecting fatigue in the task of maintaining the larger size. This condition can be intermittent or constant, and may even go away on its own without medical intervention. Simple anisocoria This is a benign condition that causes the pupils to differ in size, usually by up to one millimeter in diameter, without affecting the pupils’ response to light. The main characteristic that distinguishes physiological anisocoria is an increase of pupil size with lower light or reduced illumination, such that the pupils differ in size between the two eyes. How can you tell if anisocoria is physiological? Therefore, both pupil size and stability can objectively identify sleepiness and sleep deprivation. ![]() Aging is also a common cause of facial asymmetry. Sometimes it’s not uneven eyes, but uneven eyebrows or the shape of your nose making your eyes appear uneven. Normal facial asymmetry can make one eye appear higher or lower than the other. Why do I have one eye bigger than the other? But if it occurs suddenly, this can be a sign of a serious medical condition and you should see an eye doctor immediately. In most cases, anisocoria is mild, constant and no cause for concern. One pupil may be bigger than normal, or one pupil may be smaller than normal, resulting in unequal pupils. When should I worry about unequal pupils? It is a benign condition with a difference in pupil size of less than or equal to 1 mm. Physiologic (also known as simple or essential) anisocoria is the most common cause of unequal pupil sizes, affecting up to 20% of the population. About 15–30% of the population experiences physiological anisocoria. Physiological anisocoria may be temporary or permanent, depending on individual cases. It is the most common type of anisocoria, and the difference between the pupil sizes is no more than 1 millimeter. How rare is it to have one pupil bigger than the other? The presence of anisocoria can be normal (physiologic), or it can be a sign of an underlying medical condition. The term anisocoria refers to pupils that are different sizes at the same time. Normally the size of the pupil is the same in each eye, with both eyes dilating or constricting together. What does it mean if your pupils are 2 different sizes?
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